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The Suplagen blog

Supplements,
explained straight.

Short, practical reads on what to take, when to take it, and what to skip. No hype, no sponsorships.

LatestGuides5 min read

Supplements for cortisol: what has evidence

Cortisol fixes are all over your feed. In our catalog, one supplement has moderate evidence for lowering it, two sit at emerging, and magnesium isn't graded.

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Science5 min read

Berberine: what it actually does (and doesn't)

The internet calls berberine natural Ozempic. The evidence says something narrower: moderate support for glycemic and lipid markers, with real rules attached.

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Guides4 min read

13 supplements that need fat to absorb

Vitamin D, omega-3s, CoQ10, and 10 more supplements absorb poorly without dietary fat. The full list, and the one meal habit that fixes all of them.

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Guides5 min read

What to take on an empty stomach

Six supplements in our catalog work best before food, from rhodiola to NAC. A few others turn on you without a meal. Both lists, plus a morning that fits them.

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Safety6 min read

When more becomes worse: 10 supplement ceilings

Zinc above 40 mg costs you copper. Selenium above 400 mcg causes selenosis. The 10 supplement ceilings from our catalog, and where doubling up hides.

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Science5 min read

Why your supplement does nothing (yet)

Caffeine works in minutes, bacopa needs 12 weeks. Every supplement has a timeline, and quitting at week 3 pays for the ramp without the payoff.

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Safety6 min read

108 supplement-drug interactions, mapped

We mapped every drug interaction across our 66-supplement catalog: 108 pairs in total. Blood thinners dominate, and 54 of 66 supplements have at least one.

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Guides5 min read

Which supplements to cycle (and which not to)

Eight supplements in our catalog carry real cycling protocols. Most don't need breaks at all. The full list, the schedules, and the logic behind them.

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Guides6 min read

Build a supplement stack without wasting money

A practical order of operations: start from goals, set a pill budget, anchor everything to two doses, and review monthly. Most stacks fail at step one.

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Safety5 min read

Supplements that don't mix: pairs to space out

Calcium and iron, zinc and copper, vitamin E and K. The supplement pairs that compete or interfere, and how a morning and night split quietly solves most of it.

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Science5 min read

Magnesium glycinate, the calm one

Why glycinate became the go-to magnesium for sleep and stress: absorption, a gentle stomach, sensible dosing, and what the research actually shows.

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Science5 min read

Creatine is not just a gym supplement

The most studied supplement in the aisle: settled strength benefits, early but interesting brain research, dosing so simple it's boring, and the myths, quickly.

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Guides4 min read

Morning or night? When to take your supplements

Caffeine early, magnesium late, vitamin D with food. A short guide to supplement timing, and why two well-placed doses beat six scattered ones.

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