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Nootropics
CDP-Choline (Citicoline)
Nootropic choline source supporting brain energy and neuroprotection.
What it is
Citicoline (CDP-choline) provides both choline and cytidine, supporting acetylcholine synthesis and phospholipid membrane repair.
How it works
Donates choline for acetylcholine; cytidine converts to uridine supporting neuronal membrane phospholipid synthesis.
What the evidence says
Moderate evidence for attention and memory support; strong safety profile across clinical trials.
Safety Notes
- Generally well-tolerated. Preferred over Alpha-GPC for those sensitive to trimethylamine (fishy odor).
- cholinesterase inhibitors: Additive cholinergic effects; consult physician.
- levodopa: May enhance levodopa effects; monitor.
Timing With Other Supplements
- Alpha-GPC: Both provide choline; combining may cause excess choline symptoms (headache, GI).