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Cit
Performance

Citrulline Malate

Commonly 6–8 g pre-workout in studies; outcomes are mixed.

What it is

Citrulline malate is studied for perceived exertion and resistance exercise performance with mixed findings.

How it works

Citrulline is a precursor to arginine/nitric oxide; may influence blood flow and exercise tolerance.

What the evidence says

Mixed evidence; some studies show improved rep performance, others show no effect.

Safety Notes

  • Evidence is mixed; benefits are not universal.
  • Not recommended during pregnancy or while breastfeeding.
  • Use caution with: low blood pressure (caution).
  • nitrates / PDE5 inhibitors (caution): Potential additive vasodilation; clinician advice recommended.

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