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NAC
Amino Acids
N-Acetyl Cysteine (NAC)
Glutathione precursor; supports liver detox and respiratory health.
What it is
NAC is a stable form of the amino acid L-cysteine. It's a direct precursor to glutathione, the body's master antioxidant.
How it works
Replenishes intracellular glutathione; supports Phase II liver detoxification and mucolytic activity in airways.
What the evidence says
Strong evidence as glutathione precursor and mucolytic; moderate evidence for liver support and antioxidant defense.
Safety Notes
- May cause GI upset at higher doses. Consider taking with vitamin C to support glutathione recycling.
- Use caution with: active bleeding (caution), asthma (rare bronchospasm reported).
- nitroglycerin: May potentiate effects causing severe hypotension; avoid concurrent use.
- anticoagulants: May have mild antiplatelet effects.
- activated charcoal: Charcoal reduces NAC absorption; separate dosing.