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K2
Vitamins

Vitamin K2 (MK-7)

Directs calcium to bones; synergistic with vitamin D3.

What it is

Vitamin K2 (menaquinone-7) activates proteins that direct calcium into bones and away from arteries. Essential partner for vitamin D3 supplementation.

How it works

Activates osteocalcin (bone mineralization) and matrix Gla protein (prevents arterial calcification) via carboxylation.

What the evidence says

Moderate evidence for bone health; emerging evidence for cardiovascular protection via reduced arterial calcification.

Safety Notes

  • MK-7 form has longer half-life than MK-4. Essential if taking vitamin D3 long-term.
  • warfarin / vitamin K antagonists: Vitamin K directly opposes warfarin's mechanism; AVOID or strictly monitor INR.

Timing With Other Supplements

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