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GC
Specialty
Glucosamine + Chondroitin
Joint support complex for cartilage maintenance and comfort.
What it is
Glucosamine and chondroitin are structural components of cartilage. Supplementation aims to support joint integrity and reduce discomfort.
How it works
Glucosamine provides building blocks for glycosaminoglycans; chondroitin inhibits cartilage-degrading enzymes and supports water retention in cartilage.
What the evidence says
Moderate evidence for joint comfort in osteoarthritis; most benefit seen in moderate-to-severe cases.
Safety Notes
- Shellfish-free (vegetarian) glucosamine available. Results take 8-12 weeks. GAIT trial showed benefit mainly for moderate-to-severe knee OA.
- Use caution with: shellfish allergy (if shellfish-derived glucosamine).
- warfarin: Chondroitin may enhance anticoagulant effect; monitor INR.
- antidiabetic medications: Glucosamine may affect blood sugar; monitor.