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MSM
Specialty
MSM (Methylsulfonylmethane)
Organic sulfur compound supporting joints and inflammation.
What it is
MSM is a naturally occurring organosulfur compound. It provides bioavailable sulfur for connective tissue and has anti-inflammatory properties.
How it works
Provides sulfur for collagen/keratin synthesis; inhibits NF-κB and reduces inflammatory cytokines; supports glutathione production.
What the evidence says
Moderate evidence for joint comfort and physical function; emerging evidence for exercise recovery.
Safety Notes
- Very well tolerated. OptiMSM is a purified, patented form. Often combined with glucosamine for synergistic joint support.
- anticoagulants: Theoretical blood-thinning effect; monitor if on anticoagulants.
Timing With Other Supplements
- Glucosamine + Chondroitin: Often stacked together; complementary mechanisms for joint support.